Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome

Target users
Researchers – upon designing clinical or epidemiological studies and for reuse of data (the EXIMIOUS dataset)

Associated publications
doi: 10.1097/EE9.0000000000000193

Related downloads:

  • EXIMIOUS SOP for collection, storage and shipment of biological samples (online and PDF)
  • Collection of Blood (PDF)
  • Urine protocol (PDF)
  • README file (Plain text)

Lead partner(s)

Manosij Ghosh (KU Leuven), Unni Cecilie Nygaard (NIPH), Stephanie Humblet-Baron (KU Leuven)


Standard operating procedures (SOP) tool

A collection of protocols for the collection, storage and shipment of biological samples

The EXIMIOUS SOP tool is a collection of protocols which describe the collection, storage and shipment of biological samples for analysis of internal exposome markers.

EXIMIOUS involves collection of large amount of data, including biological samples, for the characterization of external and internal exposome markers. Samples are collected, stored and shipped at different sample collection and involves many different centers/ partner organisations. Several sample collection sites pose additional challenges such as mines and factories, and we also sampled patients in hospitals. In these complex projects, it is of crucial importance that a common, evidence-based and harmonized protocol is drafted and applied.

The EXIMIOUS SOP protocols describe the steps involved in sample collection, processing, storage and shipment. Critical steps are highlighted to assure the sample quality, which in our project was ensured by collecting and assessing sample quality of pilot samples before finalizing the SOP.