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Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome

Publications and conferences

Publications:

2023
Blanch-Perez-del-Notario, C., Geelen, B., Li Y., Vandebriel, R., Bentell, J., Jayapala, M., Charle W. (2023) Compact high-speed snapshot multispectral imagers in the VIS/NIR (460 to 960 nm) and SWIR range (1.1 to 1.65 nm) and its potential in a diverse range of applications. Hyperspectral Imaging and Applications II Vol. 12338. SPIE. doi: 10.1117/12.2664944

2022
Nygaard, U.; Ghosh, M.; Humblet-Baron, S.; Nawrot, T.; Josefsson, S.E.; Plusquin, M.; Huaux, F.; Vanoirbeek, J.; Dirven, H.; Rasmussen, P.U.; Cruz, M.; Claus, R.; Lindeman, B.; Broothaerts, K.; Hoet, P. (2022) EXIMIOUS SOP for collection, storage and shipment of biological samples (updated version 3). KU Leuven RDR. doi: 10.48804/AMZHSD

Ronsmans, S., Sørig Hougaard, K., Nawrot, T. S., Plusquin, M., Huaux, F., Jesús Cruz, M., Moldovan, H., Verpaele, S., Jayapala, M., Tunney, M., Humblet-Baron, S., Dirven, H. Cecilie Nygaard, U., Lindeman, B., Duale, N., Liston, A., Meulengracht Flachs, E., Kastaniegaard, K., Ketzel, M., Goetz, J., Vanoirbeek, J., Ghosh, M., Hoet, P. H. M, The EXIMIOUS Consortium. (2022) The EXIMIOUS project—Mapping exposure-induced immune effects: connecting the exposome and the immunome. Environmental Epidemiology 6(1), e193. doi: 10.1097/EE9.0000000000000193

Janssen, L.M.F., Ghosh, M., Lemaire, F. , Pollard, K.M., Hoet, P.H.M. (2022) Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review. Particle and Fibre Toxicology 19, 4. doi: 10.1186/s12989-021-00439-6

2021
Liston, A., Humblet-Baron, S., Duffy, D., Goris, A. (2021) Human immune diversity: from evolution to modernity. Nature Immunology 22, 1479–1489. doi: 10.1038/s41590-021-01058-1

Ronsmans, S., De Ridder, J., Vandebroek, E., Keirsbilck, S., Nemery, B., Hoet, P.H.M., Vanderschueren, S., Wuyts, W.A., Yserbyt, J. (2021) Associations between occupational and environmental exposures and organ involvement in sarcoidosis: a retrospective case-case analysis. Respiratory research 22, 224. doi: 10.1186/s12931-021-01818-5

Roca, C.P., Burton, O.T., Gergelits, V., Prezzemolo, T., Whyte, C.E., Halpert, R., Kreft, L., Collier, J., Botzki, A., Spidlen, J., Humblet-Baron, S., Liston, A. (2021) AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data. Nature Communications 12, 2890. doi: 10.1038/s41467-021-23126-8

Sánchez-Díez, S., Cruz, M-J., Álvarez-Simón, D., Montalvo, T., Muñoz, X., Hoet, P.M., Vanoirbeek, J.A., Gómez-Ollés, S. (2021) A rapid test for the environmental detection of pigeon antigen. Science of The Total Environment  778, 147789. doi:10.1016/j.scitotenv.2021.147789

Orsi, M., Palmai-Pallag, M., Yakoub, Y., Ibouraadaten, S., De Beukelaer, M., Bouzin, C., … & Huaux, F. (2021) Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes. Frontiers in Immunology 12:666107;
doi: 10.3389/fimmu.2021.666107

2020
Orsi, M., Al Hatem, C., Leinardi, R., & Huaux, F. (2020) Carbon nanotubes under scrutiny: Their toxicity and utility in mesothelioma research. Applied Sciences 10(13), 4513. doi: 10.3390/app10134513

Conference contributions:

2023
Blanch, C. Hyperspectral imaging as an exposure assessment tool. 12th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-12), 21 – 23 June 2023, Porto. Oral presentation.

Plusquin, M. A Multi-Omics Pipeline for Data Analysis, Integration and Interpretation. 12th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-12), 21 – 23 June 2023, Porto. Oral presentation.

Hoet, P. European Human Exposome Network and EXIMIOUS project. 12th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-12), 21 – 23 June 2023, Porto. Oral presentation.

Ranieri, A, Kastaniegaard, K. Omics Studio – an interactive multi-omics tool to decomplexifies and contextualize omics. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Blanch-Perez-del-Notatio, C., Bertier P., Jayapala M. Hyperspectral imaging as an exposure assessment tool. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Dornfeldt, M.M. et al. Maternal psychosocial and ergonomic strain at work during pregnancy and risk of asthma in children. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Longo Sanchez-Calero, C. et al. Inhaled silica is rapidly translocated in immune organs: an explanation of its autoimmune activities. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Sejbaek, C.S. et al. Nationwide Danish cohorts in EXIMIOUS: DOC*X and DOC*X Generation. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Kummari, E. et al. Crystalline silica particle induced immune effects on human whole blood using high dimensional immune cell profiling. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Claus, R. et al. Optimization and validation of a new custom-made activated charcoal cloth patch in real-life conditions. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Bertier, P., Verpaele, S. Occupational exposure assessments in the EXIMIOUS project: a case for the standardized compliance testing approach in epidemiological studies. EHEN Conference, 30 May – 1 June 2023, Leuven. Oral presentation.

Kummari, E. et al. Exposure Induced Immune Effects of Crystalline Silica Particles on Whole Blood using High Dimensional Immune Cell Profiling. Society of Toxicology (SOT2023), 1 April 2023, Nashville. Poster.

Ghosh, M. et al. FAIR Data management in exposome research – a case study from the EU-funded EXIMIOUS project. EPICOH 2023, 14-17 March 2023, Mumbai. Oral presentation.

2022
Lindeman, B. et al. Immunotoxicity of crystalline silica particles: in vitro screening models and use of high- dimensional immune cell profiling. ESTIV, 21-25 November 2022. Oral presentation.

Blanch, C. et al. Compact high-speed snapshot multispectral imagers in the VIS/NIR (460-960 nm) and SWIR range (1.1-1.65 nm) and its potential in a diverse range of applications. SPIE Photonex, 12 June 2022, Birmingham. Oral presentation.

Ghosh, M. EXIMIOUS: Connecting the Exposome and the Immunome. RISE 2022 – 5th International Meeting on Environmental Health, 6 September 2022, Strasbourg.

Ranieri, A. et al. Artificial Intelligence for exploring associations between occupational exposures and autoimmune disease. EHEN Scientific Meeting, 24-25 May 2022, Barcelona. Oral presentation.

Madsen, A.M. et al. Association between markers of inflammation and exposure to endotoxin as measured using different methods. EHEN Scientific Meeting, 24-25 May 2022, Barcelona. Oral presentation.

Longo, C. et al. Exposure to silica: what does biomonitoring tell us?EHEN Scientific Meeting, 24-25 May 2022, Barcelona. Oral presentation.

Claus, R. et al. Assessment of occupational exposure to styrene in a Fibreglass Reinforced Plastics Industry. EHEN Scientific Meeting, 24-25 May 2022, Barcelona. Oral presentation.

Troeyer, K. de et al. Identifying cleaning products associated with short-term work-related respiratory symptoms: a workforce-based study in domestic cleaners. EHEN Scientific Meeting, 24-25 May 2022, Barcelona. Oral presentation.

2021

Janssen, L.M.F. The EXIMIOUS project-Mapping exposure-induced immune effects: connecting the exposome and the immunome. International Exposome Conference 2021, 29 November 2021, Online. Oral presentation.

Vanoirbeek, J. Dermal exposure vs inhalation exposure: what is the relative contribution to the internal dose? BSOH webinar: Occupational hygiene in the Exposome context: are sensors the future for measuring?, 12 November 2021, Online. Oral presentation.

Blanch, C. Exposure assessment using spectral imaging techniques. BSOH webinar: Occupational hygiene in the Exposome context: are sensors the future for measuring?, 12 November 2021, Online. Oral presentation.

Vanoirbeek, J. Skin exposure to chemicals and the relative contribution to the internal dose. EXIMIOUS-EPHOR joint symposium at IETOX 2021, 4-7 November 2021, Online. Oral presentation.

Nygaard, U.C. CyTOF data for exploring cellular immune profiles – to illustrate how it will be used in the EXIMIOUS project. EXIMIOUS-EPHOR joint symposium at IETOX 2021, 4-7 November 2021, Online. Oral presentation.

Vanoirbeek, J. Dermal exposure vs inhalation exposure: what is the relative contribution to the internal dose? EXIMIOUS-EPHOR joint symposium at IOHA 2021, 11-15 September 2021, Online. Oral presentation.

Jayapala, M. Exposure assessment using spectral imaging techniques – possibilities in EU EXIMIOUS project and beyond. EXIMIOUS-EPHOR joint symposium at IOHA 2021, 11-15 September 2021, Online. Oral presentation.

Vanoirbeek, J. Using sensors to study the exposome: Dermal patches to assess skin exposure. EHEN conference: decoding the exposome, 11 June 2021, Online. Oral presentation.

Nawrot, T. The chemical exposome (new methods): Measuring black carbon in people. EHEN conference: decoding the exposome, 11 June 2021, Online. Oral presentation.

Croons, H. The Lifelines cohort at Uhasselt. EHEN network day, 16 March 2021, Online. Oral presentation.

2020
Hoet, P. Presentation of EXIMIOUS. KU Leuven – Horizon 2020 Launch Event, 11 December 2020, Online. Oral presentation.

Hoet, P. Presentation of EXIMIOUS. Launch event of the European Human Exposome Network, 11 February 2020, European Commission Brussels, Belgium. Oral presentation.